Swertiamarine

Inquiry

For Research Use Only.

Category

Phenols

Cat.No.

NP4611

CAS

55481-88-4

Product Name

Swertiamarine

Structure

Product Details

Description

Mollugin, which can be extracted from the roots of Rubia cordifolia L, could be a novel therapeutic candidate for bone loss-associated disorders including osteoporosis, rheumatoid arthritis, and periodontitis. It is a novel modulator of the HER2 pathway in HER2-overexpressing cancer cells with a potential role in the treatment and prevention of human breast and ovarian cancer with HER2 overexpression. Besides, Mollugin may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation of the JAK-STAT pathway.

Synonyms

Rubimaillin; 2H-Naphtho[1,2-b]pyran-5-carboxylic acid; 6-hydroxy-2, 2-dimethyl-, methylester; 2,2-Dimethyl-6-hydroxy-2H-naphtho[1,2-b]pyran-5-carboxylic acid methyl ester; 6-Hydroxy-2,2-dimethyl-2H-naphtho[1,2-b]pyran-5-carboxylic acid methyl ester; Methyl 6-hydroxy-2,2-dimethylbenzo[h]chromene-5-carboxylate; MOLLUGIN(SH)

Molecular Weight

284.3

Molecular Formula

C17H16O4

Boiling Point

453.2±45.0 °C(Predicted)

Melting Point

132~134 °C

Purity

>98%

Density

1.239±0.06 g/cm3(Predicted)

Solubility

Chloroform (Slightly), Ethyl Acetate (Slightly)

Appearance

Cryst.

Application

Anticancer

Storage

2-8°C

Color

Yellow to Green

EINECS

683-209-5

Form

Solid

HS Code

29329990

pKa

8.40±0.40(Predicted)

Safety Statements

24/25

Uses

Mollugin is an anti-tumor agent inducing apoptosis and autophagy in various cancer models.

Products

Inquiry

* Name:
* Phone:
* Quantity
* Email:
* Service & Products of Interested: [Phenols] Swertiamarine (55481-88-4)
Project Description:
* Verification Code:
SUBMIT