The purpose of natural product extraction is to obtain crude extracts containing the target natural products from natural raw materials, which is the first step in the separation and purification of natural products. In the process of natural product extraction, the diffusivity and solubility of solutes in the solvent are the key factors affecting the extraction rate, i.e. any conditions that promote the diffusion or solubility of solutes in the solvent can increase their extraction rate. Currently, we use extraction methods that generally improve the extraction rate of the target product by auxiliary means such as pressurization, such as supercritical fluid extraction, pressurized liquid extraction and microwave-assisted extraction, which save solvent, shorten extraction time and have high selectivity. BOC Sciences has a wide range of specialized natural product extraction technologies for many different kinds of natural products.
Grinding, high pressure homogenization, ultrasound, filtration, centrifugation, drying, etc.
Freeze dissolution, dialysis, ultrafiltration reverse osmosis, flocculation, extraction, adsorption, chromatography (adsorption chromatography, partition chromatography, gel chromatography), distillation, electrophoresis, isoelectric point precipitation, salinization, crystallization, etc.
Ion exchange, chemical precipitation, chemical affinity, etc.
Bioaffinity chromatography, immunochromatography, etc.
Microwave, ultrasonic extraction, resin adsorption separation, microfiltration, ultrafiltration, nanofiltration, affinity membrane separation, foam separation, supercritical fluid extraction, molecular distillation, double aqueous phase separation, anticellular beam extraction, etc.
Microbiological engineering and biological cell tissue culture engineering technology, enzyme engineering technology, etc.
BOC Sciences can provide services for the extraction of natural products, as well as the design and optimization of extraction processes. After the extraction of natural products, we can also perform qualitative and quantitative analysis of the extracts, providing a complete service process for our customers. Currently, we have developed the following natural product extraction services.
BOC Sciences offers extraction process design services for natural products based on customer requirements. Our biological and chemical researchers will design the extraction process based on the biological microstructure, the structure of the natural product, and the coupling of different separation techniques to help our clients quickly select the extraction technology with high extraction efficiency and yield.
Based on the existing experimental equipment and rich experience in extraction, BOC Sciences provides extraction process optimization by orthogonal experimental design method and response surface experimental design method. The most suitable extraction solution is selected for the customer through optimization.
The extracts can be analyzed qualitatively and quantitatively by gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-mass spectrometry (LC-MS), and the percentage content of each component can be calculated by normalization method.
In addition to the above extraction process-related services, our research team also provides professional natural product refining, separation, purification, and structure identification services to provide comprehensive and integrated services for our customers and help them complete their product development efficiently.
If you have a requirement about our services, please contact us by phone or email, our colleagues will reply to you within three working days.