Inflammation is a defensive response of living tissues with a vascular system to injury factors and is involved in the pathogenesis of many diseases. A variety of key enzymes and factors in cell signaling pathways are involved, such as nuclear factor NF-xB, mitogen-activated proteases, matrix metalloproteinases, and the STAT nuclear protein family, which plays a key role in the growth hormone signaling pathway. A variety of natural products obtained from plants have anti-inflammatory activities, which are characterized by diverse structures and activities, wide range of action targets and low toxic side effects. BOC Sciences can provide testing of a wide range of natural products in the direction of anti-inflammatory activity to help customers quickly locate and analyze the active ingredients in natural products for anti-inflammation.
Terpenoids are one of the most abundant and well-studied classes of natural products. They are widely sourced and have a variety of important pharmacological activities, including anti-inflammatory, making them an important resource for new drug development.
Flavonoids are widely found in many common fruits, vegetables and herbs, and there is growing evidence that flavonoids have anti-inflammatory activity and inhibitory effects on inflammatory factors.
Polysaccharides are formed by condensation and water loss of several monosaccharide molecules, and are a class of biomacromolecular compounds with complex molecular structures. Polysaccharides have diverse biological activities such as immune enhancement, anti-inflammatory and anti-viral.
The prepared cell suspensions were incubated in an incubator, and the natural products were added afterwards. The absorbance value is measured and the inhibition rate is calculated.
The toxicity and pro-inflammatory factors of the cell model are tested, and the natural product is added. The activity of the natural products is confirmed (inflammatory factor and protease expression assay), and the active components that can inhibit inflammatory factors are screened.
BOC Sciences is an innovator and manufacturer of natural products, and we meet the market demand for natural product monomers. Our expert team has extensive experience in all synthesis stages and has successfully contributed numerous compounds for the fields of medicine, agriculture and environment. The production, testing, packaging and release of all compounds follow strict specifications. If you have a requirement about our services, please contact us by phone or email, our colleagues will reply to you within three working days.