The basic principle of simulated moving bed adsorption is similar to that of adsorption and desorption moving bed, and its main feature is that the adsorption bed is fixed and the position of the material port is continuously changed to simulate the counter-current contact between solid adsorbent and liquid. It connects multiple chromatographic columns with multi-bit valves and tubes, and each column is equipped with the inlet and outlet of the sample, and changes the inlet and outlet position of the sample by continuously changing forward along the flow direction of the mobile phase by multi-bit valves, so as to simulate the counter-current movement between the stationary phase and the mobile phase and realize the continuous separation of the two components.

Advantages of Simulated Moving Bed Chromatography Systems

• Higher productivity and purity compared to batch systems, even for small SMB systems.
• 90% solvent savings and 80% solid phase cost reduction.
• Obtain almost pure product and reduce concentration efforts.

Our Services

BOC Sciences' simulated moving bed (SMB) chromatography can be used to develop new processes or for scale-up installations. Here, we can develop new applications and perform testing for our customers. We perform trials and pre-studies of laboratory-scale simulated moving bed (SMB) chromatography, whose compact design is particularly suitable for small-volume separation tasks.

Service content

• Separation of natural products (plant proteins)
• Optimization of product solutions

Applications of Simulated Moving Bed Chromatography

Potential applications range from conventional simulated moving bed SMB separations for the natural products industry to innovative processes for the fine chemistry and biotechnology industries. We can support you every step of the way: from process development in our mobile laboratory, to pilot facilities and turnkey plant installations.

Our Advantages

• Short experimental cycle times and fast delivery of content.
• Good prices, because we offer an integrated service that reduces many intermediate processes.
• Perfect after-sales service; you can always consult us to get the information you want.
• Rich project experience, mature technical system and professional scientific staff.
• A complete set of experimental services, from sample separation and purification and various types of analysis to final data reporting.

About Us

BOC Sciences is an innovator and manufacturer of natural products, and we meet the market demand for natural product monomers. Our expert team has extensive experience in all synthesis stages and has successfully contributed numerous compounds for the fields of medicine, agriculture and environment. The production, testing, packaging and release of all compounds follow strict specifications. If you have a requirement about our services, please contact us by phone or email, our colleagues will reply to you within three working days.

• High Performance Liquid Chromatography Services
• Ion Exchange Chromatography Services
• Gel Filtration Chromatography Services
• Thin Layer Chromatography Services
• Partition Chromatography Services
• Adsorption Chromatography Services