Description
It is produced by the strain of Str. rimosus, Str. gilvus. It has anti-gram-positive bacteria, negative bacteria, mycobacterium effects. It also has inhibitory effect on mycoplasma, rickettsia, chlamydia, spirochetes and some protoplasm. It has been used clinically. It was cross-resistant to tetracycline and aureomycin, and partially resistant to chloramphenicol.
Synonyms
Biosolvomycin; Engemycin; Oxamycen; Terramycin hydrochloride; Bisolvomycin; Dalimycin; Unimycin
IUPAC Name
(4S,4aR,5S,5aR,6S,12aR)-4-(dimethylamino)-1,5,6,10,11,12a-hexahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;hydrochloride
Molecular Formula
C22H24N2O9.HCl
Canonical SMILES
CC1(C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O)O.Cl
InChI
1S/C22H24N2O9.ClH/c1-21(32)7-5-4-6-8(25)9(7)15(26)10-12(21)17(28)13-14(24(2)3)16(27)11(20(23)31)19(30)22(13,33)18(10)29;/h4-6,12-14,17,25-26,28,30,32-33H,1-3H3,(H2,23,31);1H/t12-,13-,14+,17+,21-,22+;/m1./s1
InChIKey
SVDOODSCHVSYEK-IFLJXUKPSA-N
Boiling Point
839.6°C at 760 mmHg
Solubility
Soluble in Methanol, Ethanol, DMF, DMSO, Water
Appearance
Yellow Crystalline Solid
Application
Antibiotic substance isolated from the elaboration products of the actinomycete, Streptomyces rimosus, grown on a suitable medium. Antibacterial.
Vapor Pressure
2.17E-30mmHg at 25°C