Description
Obtusifolin, a major bioactive compound present in Cassia tora L., suppressed phthalate esters-mediated bone resorption. Therefore, Obtusifolin may be a novel anti-breast-cancer bone metastasis agent. Obtusifolin has antioxidant properties and improves chemically induced diabetes and its complications by modulation of oxidative stress. Besides, Obtusifolin and gluco-Obtusifolin produce significant antinociceptive action in rodent behavioral models of inflammatory/neuropathic pain, and that this activity is associated with modulation of neuroinflammation in spinal cord.
Synonyms
2,8-Dihydroxy-1-methoxy-3-methyl-9,10-anthracenedione; 9,10-Anthracenedione, 2,8-dihydroxy-1-methoxy-3-methyl-; Anthraquinone, 2,8-dihydroxy-1-methoxy-3-methyl-; Obtusifolin (anthraquinone); 2,8-Dihydroxy-1-Methoxy-3-Methylanthraquinone