Erlotinib hydrochloride

Name: Erlotinib hydrochloride
Brand: BOC Sciences
Price: 199 USD
Availability: MadeToOrder

Inquiry

For Research Use Only.

Category

Impurities

Cat.No.

NP3672

CAS

183319-69-9

Product Name

Erlotinib hydrochloride

Structure

Product Details

Description

Erlotinib HCl potently inhibits EGFR activation in intact cells including HNS human head and neck tumor cells (IC50 = 20 nM), DiFi humancolon cancer cells and MDA MB-468 human breast cancer cells.

Synonyms

OSI-744; OSI744; OSI 744; Tarceva; 4-(m-Ethynylanilino)-6,7-bis(2-methoxyethoxy)quinazoline monohydrochloride; 6,7-bis(2-methoxyethoxy)-4-(3-ethynylanilino)quinazoline hydrochloride

IUPAC Name

N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine;hydrochloride

Molecular Weight

429.90

Molecular Formula

C22H23N3O4.HCl

Canonical SMILES

COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C#C)OCCOC.Cl

InChI

InChI=1S/C22H23N3O4.ClH/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22;/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25);1H

InChIKey

GTTBEUCJPZQMDZ-UHFFFAOYSA-N

Boiling Point

553.6°C at 760 mmHg

Melting Point

223-225°C

Purity

>98%

Solubility

Soluble in Acetic Acid, Dimethylformamide, Dimethyl Sulfoxide, Methanol

Appearance

Off-white Solid