Description
Aristolactam BII, a natural alkaloid isolated from the herbs of Aristolochia debilis Sieb. et Zucc exhibits significant activities in the anti-syncytium assay using (ΔTat/Rev)MC99 virus and 1A2 cell line system. By directly inhibiting the production of nitric oxide, aristolactam BII exerts its significant neuroprotective effects on glutamate-injured primary cultures of rat cortical cells.