Wighteone

Inquiry

For Research Use Only.

Size	Price	Stock	Quantity
1 mg	$439	In stock

Category

Flavonoids

Cat.No.

NP2444

CAS

51225-30-0

Product Name

Wighteone

Structure

Product Details

Description

Wighteone, also called Erythrinin B, is a natural flavonoid isolated from the herbs of Glycyrrhiza glabra, has a potent anti-proliferative effect on human leukemia HL-60 cancer cell lines, it can effectively inhibit the proliferation of HER2-positive cancer cell lines, which is considered to be the result of downregulating HSP90 receptor and downstream signaling. Wighteone also exhibits cytocidal activity against KB cells in vitro.

Synonyms

3-(4-Hydroxyphenyl)-5,7-dihydroxy-6-(3-methyl-2-butenyl)-4H-1-benzopyran-
4-one;4',5,7-Trihydroxy-6-(3-methyl-2-butenyl)isoflavone;4',5,7-Trihydroxy-6-prenyl-isofla
vone;5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one;
Eryth

IUPAC Name

5,7-dihydroxy-3-(4-hydroxyphenyl)-6-(3-methylbut-2-enyl)chromen-4-one

Molecular Weight

338.4

Molecular Formula

C20H18O5

Canonical SMILES

CC(=CCC1=C(C2=C(C=C1O)OC=C(C2=O)C3=CC=C(C=C3)O)O)C

InChI

InChI=1S/C20H18O5/c1-11(2)3-8-14-16(22)9-17-18(19(14)23)20(24)15(10-25-17)12-4-6-13(21)7-5-12/h3-7,9-10,21-23H,8H2,1-2H3

InChIKey

KIMDVVKVNNSHGZ-UHFFFAOYSA-N