Venlafaxine hydrochloride

Impurities

NP3427

99300-78-4

Venlafaxine hydrochloride

Venlafaxine hydrochloride is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class, but it has been referred to as a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI). It is licensed for the treatment of major depressive disorder (MDD), as a treatment for generalized anxiety disorder, and comorbid indications in certain anxiety disorders with depression. It works by blocking the transporter reuptake proteins for key neurotransmitters affecting mood, thereby leaving more active neurotransmitters in the synapse. It can increase dopamine neurotransmission in this part of the brain. It is seemingly superior efficacy in severe depression as narcotics become increasingly used as a measure of last resort for refractory cases.

Wy-45030; Wy45030; Wy 45030; Effexor hydrochloride; Effexor; VENLAFAXINE HCl; Effexor XR; Trevilor

1-[2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexan-1-ol;hydrochloride

313.86

C17H28ClNO2

CN(C)CC(C1=CC=C(C=C1)OC)C2(CCCCC2)O.Cl

InChI=1S/C17H27NO2.ClH/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14;/h7-10,16,19H,4-6,11-13H2,1-3H3;1H

QYRYFNHXARDNFZ-UHFFFAOYSA-N

207-209°C

>98%

White Solid

antidepressant

10 g