Uvaol

Inquiry

For Research Use Only.

Category

Terpenes

Cat.No.

NP6317

CAS

545-46-0

Product Name

Uvaol

Structure

Product Details

Description

Uvaol, also called urs-12-ene-3β,28-diol is a natural triterpenoid found in the herbs of Callicarpa bodinieri Levl. Urs-12-ene-3β,28-diol exhibits the activity of anti-inflammatory. Urs-12-ene-3β,28-diol also has has anti-proliferative activity,inhibits the angiotensin II-induced proliferation in a PPAR-γ-dependent manner, while at high doses they activate pathways of programmed cell death that are dependent on JNK and PPAR-γ.

Synonyms

Urs-12-ene-3β,28-diol

Molecular Weight

442.7

Molecular Formula

C30H50O2

Canonical SMILES

CC1(C)[C@@H](O)CC[C@]2(C)[C@@]3([H])CC=C4[C@]5([H])[C@@H](C)[C@H](C)CC[C@@](CO)5CC[C@](C)4[C@@](C)3CC[C@@]12[H]

InChI

1S/C30H50O2/c1-19-10-15-30(18-31)17-16-28(6)21(25(30)20(19)2)8-9-23-27(5)13-12-24(32)26(3,4)22(27)11-14-29(23,28)7/h8,19-20,22-25,31-32H,9-18H2,1-7H3/t19-,20+,22+,23-,24+,25+,27+,28-,29-,30-/m1/s1

InChIKey

XUARCIYIVXVTAE-ZAPOICBTSA-N

Boiling Point

523.7±50.0 °C(Predicted)

Melting Point

223-225 °C (lit.)

Purity

>98%

Density

1.05 g/cm3

Solubility

Chloroform (Slightly), Ethyl Acetate (Slightly)

Appearance

Powder

Application

anti-inflammatory; anti-proliferative

Storage

-20°C Freezer

Color

White to Off-White

Definition

ChEBI: A natural product found in Rhododendron ferrugineum.

EINECS

208-888-3

Form

Solid

pKa

15.09±0.10(Predicted)

Risk Statements

Safety Statements

22-45

Uses

Uvaol can attenuate pleuritis and eosinophillic inflammation in mice that is induced by ovalbumin. It is an essential reagent in the synthesis of aminopropoxytriterpenoids that have anticancer activity.

WGK Germany

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