Ursolic acid

For Research Use Only.
Category
Triterpenoids
Cat.No.
NP6978
CAS
77-52-1
Product Name
Ursolic acid
Structure

Product Details

Description
Ursolic acid is a natural pentacyclic triterpenoid carboxylic acid displaying antitumor activity. It was shown to downregulate the MMP-2 and uPA expression, and also inhibit Na+/K+-ATPase activity (IC50 = 24.7 μM) as well as NF-κB activation in various cancer cell lines. Ursolic acid can induce apoptosis in cancer cells. Ursolic acid also has obvious antioxidant function, so it is widely used as a raw material for medicine and cosmetics.
Synonyms
NSC-167406, NSC-4060, NSC167406, NSC4060, NSC 167406, NSC 4060; Malol; Prunol; Urson; 3beta-Hydroxyurs-12-en-28-oic acid
Molecular Weight
456.711
Molecular Formula
C30H48O3
Canonical SMILES
CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)O)C)C)C2C1C)C)C(=O)O
InChI
InChI=1S/C30H48O3/c1-18-10-15-30(25(32)33)17-16-28(6)20(24(30)19(18)2)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h8,18-19,21-24,31H,9-17H2,1-7H3,(H,32,33)/t18-,19+,21+,22-,23+,24+,27+,28-,29-,30+/m1/s1
InChIKey
WCGUUGGRBIKTOS-GPOJBZKASA-N
Boiling Point
556.9±50.0 °C at 760 mmHg
Melting Point
280 °C-290 °C;
Flash Point
304.6°C
Purity
≥ 98%
Density
1.09 g/cm³
Solubility
About 0.5% in Ethanol, More than 2.5% in DMSO; Practically insoluble in water.
Appearance
Powder
Application
antidepressant
Storage
Store in a freezer upon arrival, at -10°C to -25°CUse the original container to store the product.Keep the lid tightly closed.Avoid exposing to strong direct light.Other vendors may recommend higher temperatures for storage.
Form
Powder
Packaging
25 g
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