Description
Tuberstemonine, coming from the roots of Stemona japonica, exhibited relatively higher intestinal permeabilities. It acts in part as an open-channel blocker at the crayfish neuromuscular junction.
Synonyms
(7aR,8aβ,11aβ,11bα,11cβ)-2β-[(2S,4S)-Tetrahydro-4-methyl-5-oxofuran-2-yl]-8β-ethyltetradecahydro-11β-methylfuro[2,3-h]pyrrolo[3,2,1-jk][1]benzoazepine-10-one; 2β-[(2S,4S)-Tetrahydro-4-methyl-5-oxofuran-2-yl]stenine; TUBERSTEMONINE(P)
IUPAC Name
(1R,3S,9R,10R,11S,14S,15S,16R)-10-ethyl-14-methyl-3-[(2S,4S)-4-methyl-5-oxooxolan-2-yl]-12-oxa-4-azatetracyclo[7.6.1.04,16.011,15]hexadecan-13-one
Molecular Formula
C22H33NO4
Canonical SMILES
CCC1C2CCCCN3C2C(CC3C4CC(C(=O)O4)C)C5C1OC(=O)C5C
InChI
InChI=1S/C22H33NO4/c1-4-13-14-7-5-6-8-23-16(17-9-11(2)21(24)26-17)10-15(19(14)23)18-12(3)22(25)27-20(13)18/h11-20H,4-10H2,1-3H3/t11-,12-,13+,14+,15+,16-,17-,18+,19+,20-/m0/s1
InChIKey
GYOGHROCTSEKDY-JJDZUBOLSA-N
Application
Anti-inflammatory/anti-bacterial/anti-allergy