Triptoquinone B

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For Research Use Only.
Category
Diterpenoids
Cat.No.
NP1268
CAS
142937-50-6
Product Name
Triptoquinone B
Structure

Product Details

Description
Triptoquinone B, also called 19-Hydroxy-8,12-abietadiene-3,11,14-trione, is a natural diterpenoid found in the vines of Tripterygium wilfordii. 19-Hydroxy-8,12-abietadiene-3,11,14-trione is a novel interleukin-1 inhibitor, shows extremely potent inhibitory activities against interleukin-lα and β releases for human peripheral mononticlear cells.
Synonyms
19-Hydroxy-8,12-abietadiene-3,11,14-trione
IUPAC Name
(4bS,8S,8aR)-8-(hydroxymethyl)-4b,8-dimethyl-2-propan-2-yl-6,8a,9,10-tetrahydro-5H-phenanthrene-1,4,7-trione
Molecular Weight
330.4
Molecular Formula
C20H26O4
Canonical SMILES
CC(C)C1=CC(=O)C2=C(C1=O)CCC3C2(CCC(=O)C3(C)CO)C
InChI
InChI=1S/C20H26O4/c1-11(2)13-9-14(22)17-12(18(13)24)5-6-15-19(17,3)8-7-16(23)20(15,4)10-21/h9,11,15,21H,5-8,10H2,1-4H3/t15-,19+,20-/m1/s1
InChIKey
RYYRZMIBKOKIRO-UIAACRFSSA-N
Purity
>98%
Appearance
Powder
Definition
ChEBI: An abietane diterpenoid with formula C20H26O4, originally isolated from Tripterygium wilfordii.
Form
Powder
Packaging
1 mg
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