Description
The roots of Tripterygium wilfordii Hook. f.
Synonyms
Phenanthro(1,2-c)furan-1(3H)-one, 3b,4,5,9b,10,11-hexahydro-6-hydroxy-9b-methyl-7-(1-methylethyl)-, (3bR-trans)-
Molecular Formula
C20H24O3
Canonical SMILES
CC(C)C1=C(C2=C(C=C1)[C@]3(CCC4=C([C@@H]3CC2)COC4=O)C)O
InChI
InChI=1S/C20H24O3/c1-11(2)12-4-6-16-14(18(12)21)5-7-17-15-10-23-19(22)13(15)8-9-20(16,17)3/h4,6,11,17,21H,5,7-10H2,1-3H3/t17-,20+/m0/s1
InChIKey
CC(C)C1=C(C2=C(C=C1)C3(CCC4=C(C3CC2)COC4=O)C)O
Boiling Point
490.0±45.0 °C | Condition: Press: 760 Torr
Density
1.21±0.1 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr
Application
triptophenolide can remarkably inhibit the delayed type hypersensitivity (DTH) reaction induced by DNCB and BSA in vitro. It also could diminishe the peripheral blood ANAE+lymphocytes in rats and micc. It can significautly increase the amount of total serum complement and dramatically decrcase the serum antibody products (1gG ) of rats and mice.
Shelf Life
2 month in rt, long time