Description
Tripterifordin is isolated from the roots of Tripterygium wilfordii.
Synonyms
Tripterifordin; 139122-81-9; Hypodiolide A; (1R,2R,5R,6R,8S,11S,12R)-6-hydroxy-6,12-dimethyl-14-oxapentacyclo[10.3.3.15,8.01,11.02,8]nonadecan-13-oneKauran-18-oic acid, 16,20-dihydroxy-, delta-lactone, (4alpha)-
IUPAC Name
(1R,2R,5R,6R,8S,11S,12R)-6-hydroxy-6,12-dimethyl-14-oxapentacyclo[10.3.3.15,8.01,11.02,8]nonadecan-13-one
Molecular Formula
C20H30O3
Canonical SMILES
CC12CCCC3(C1CCC45C3CCC(C4)C(C5)(C)O)COC2=O
InChI
InChI=1S/C20H30O3/c1-17-7-3-8-20(12-23-16(17)21)14(17)6-9-19-10-13(4-5-15(19)20)18(2,22)11-19/h13-15,22H,3-12H2,1-2H3/t13-,14-,15-,17-,18-,19+,20+/m1/s1
InChIKey
KLMZPLYXGZZBCX-CJSYXLNHSA-N
Boiling Point
485.1±45.0 °C at 760 mmHg
Flash Point
198.6±21.5 °C
Solubility
In vitro:
10 mM in DMSO
Definition
ChEBI: A kaurane diterpenoid that is (5beta,8alpha,13alpha)-18,20-epoxykauran-18-one substituted by a hydroxy group at position 16. Isolated from the roots of Tripterygium wilfordii, it exhibits anti
HIV activity.
pKa
15.24±0.40(Predicted)
Vapor Pressure
0.0±2.8 mmHg at 25°C