Tormentic acid

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For Research Use Only.

Size	Price	Stock	Quantity
2 mg	$187	In stock

Category

Terpenes

Cat.No.

NP6588

CAS

13850-16-3

Product Name

Tormentic acid

Structure

Product Details

Description

Tormentic acid is a terpenoid isolated from the herb of Potentilla tormentilla. It inhibits LPS-induced iNOS, COX-2, and TNF-α expression through inactivation of the nuclear factor-κb pathway in RAW 264.7 macrophages.

Synonyms

Jacarandic acid; (1R,2R,4aS,6aR,6aS,6bR,8aR,10R,11R,12aR,14bS)-1,10,11-trihydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid; 2α,19α-Dihydroxyursolic acid

Molecular Weight

488.709

Molecular Formula

C30H48O5

Canonical SMILES

CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)C)O)O)C)C)C2C1(C)O)C)C(=O)O

InChI

InChI=1S/C30H48O5/c1-17-10-13-30(24(33)34)15-14-27(5)18(22(30)29(17,7)35)8-9-21-26(4)16-19(31)23(32)25(2,3)20(26)11-12-28(21,27)6/h8,17,19-23,31-32,35H,9-16H2,1-7H3,(H,33,34)/t17-,19-,20+,21-,22-,23+,26+,27-,28-,29-,30+/m1/s1

InChIKey

OXVUXGFZHDKYLS-BLIWDXROSA-N

Boiling Point

602.7±55.0 °C at 760 mmHg

Melting Point

273 °C

Purity

>98%

Density

1.2±0.1 g/cm3

Solubility

Pyridine (Sparingly)

Appearance

Solid Powder

Storage

Sealed in dry,Room Temperature

Color

White to Off-White

Form

Solid

pKa

4.47±0.70(Predicted)

Uses

Tormentic Acid is isolated from Tormentil rhizomes and has inhibitory effect on carcinognenesis. In addition, Tormentic Acid has been implicated to be a potential therapeutic candidate for the prevention of APAP-induced liver injury by inhibiting oxidative stress and inflammation.

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