Toddaculin

Inquiry

For Research Use Only.

Category

Coumarins

Cat.No.

NP1046

CAS

4335-12-0

Product Name

Toddaculin

Structure

Product Details

Description

Toddaculin may be beneficial for the prevention and treatment of osteoporosis, it can not only inhibit the differentiation of osteoclasts via activation of the NF-B, ERK 1/2, and p38 MAPK signaling pathways, but can induce differentiation and mineralization of osteoblasts by regulating differentiation factors. Toddaculin is also a natural coumarin that can induce differentiation and apoptosis in leukemic cells.

Synonyms

Toddaculine; 2H-1-Benzopyran-2-one, 5,7-dimethoxy-6-(3-methyl-2-butenyl)-; 6-(3-Methyl-2-butenyl)-5,7-dimethoxy-2H-1-benzopyran-2-one

IUPAC Name

5,7-dimethoxy-6-(3-methylbut-2-enyl)chromen-2-one

Molecular Weight

274.31

Molecular Formula

C16H18O4

Canonical SMILES

CC(=CCC1=C(C=C2C(=C1OC)C=CC(=O)O2)OC)C

InChI

InChI=1S/C16H18O4/c1-10(2)5-6-11-13(18-3)9-14-12(16(11)19-4)7-8-15(17)20-14/h5,7-9H,6H2,1-4H3