δ-Tocotrienol

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For Research Use Only.

Size	Price	Stock	Quantity
50 mg	$299	In stock
100 mg	$512	In stock

Category

Phenols

Cat.No.

NP4617

CAS

25612-59-3

Product Name

δ-Tocotrienol

Structure

Product Details

Description

δ-Tocotrienol is from palm oil. Delta-tocotrienol is a potential angiogenic inhibitor that significantly suppresses human colorectal adenocarcinoma cells (DLD-1-CM)-induced tube formation, migration, and adhesion on human umbilical vein endothelial cells. Delta-tocotrienol is a nontoxic activator of mir-34a which can inhibit nonsmall cell lung cancer cells (NSCLC) cell proliferation, induce apoptosis and inhibit invasion, and thus offer a potential starting point for the design of novel anticancer agents. Delta-tocotrienol displays significant radioprotective effects that protects mouse and human hematopoietic progenitors from gamma-irradiation through extracellular signal-regulated kinase/mammalian target of rapamycin signaling.

Synonyms

[R-(E,E)]-3,4-Dihydro-2,8-dimethyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-2H-1-benzopyran-6-ol; (2R)-3,4-Dihydro-2,8-dimethyl-2-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrienyl]-2H-1-benzopyran-6-ol; 2,8-Dimethyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-6-chromanol; (R)-δ-Tocotrienol; 8-Methyltocotrienol; d-δ-Tocotrienol

IUPAC Name

(2R)-2,8-dimethyl-2-[(3E,7E)-4,8,12-trimethyltrideca-3,7,11-trienyl]-3,4-dihydrochromen-6-ol

Molecular Weight

396.60

Molecular Formula

C27H40O2

Canonical SMILES

CC1=CC(=CC2=C1OC(CC2)(C)CCC=C(C)CCC=C(C)CCC=C(C)C)O

InChI

InChI=1S/C27H40O2/c1-20(2)10-7-11-21(3)12-8-13-22(4)14-9-16-27(6)17-15-24-19-25(28)18-23(5)26(24)29-27/h10,12,14,18-19,28H,7-9,11,13,15-17H2,1-6H3/b21-12+,22-14+/t27-/m1/s1

InChIKey

ODADKLYLWWCHNB-LDYBVBFYSA-N

Boiling Point

517.3±39.0 °C(Predicted)

Purity

95%

Density

0.968±0.06 g/cm3(Predicted)

Solubility

Soluble in Chloroform (Sparingly), Methanol (Slightly)

Appearance

Liquid

Storage

-20°C

Color

Pale Yellow to Orange to Thick

Definition

ChEBI: A tocotrienol that is chroman-6-ol substituted by methyl groups at positions 2 and 8 and a farnesyl chain at position 2.

Form

Neat

HS Code

29061990

pKa

10.69±0.40(Predicted)

Stability

Light Sensitive

Uses

δ-Tocotrienol is a natural substance with vitamin E activity. It can work as an antioxidant. It inhibits the growth of human breast cancer cells.

WGK Germany

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