Description
Thiamphenicol is an antimicrobial antibiotic and a methyl-sulfonyl analogue of chloramphenicol. Thiamphenicol is used to treat chicken intestinal infections caused by E. coli.
IUPAC Name
2,2-dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide
Molecular Formula
C12H15Cl2NO5S
Canonical SMILES
CS(=O)(=O)C1=CC=C(C=C1)C(C(CO)NC(=O)C(Cl)Cl)O
InChI
InChI=1S/C12H15Cl2NO5S/c1-21(19,20)8-4-2-7(3-5-8)10(17)9(6-16)15-12(18)11(13)14/h2-5,9-11,16-17H,6H2,1H3,(H,15,18)/t9-,10-/m1/s1
InChIKey
OTVAEFIXJLOWRX-NXEZZACHSA-N
Boiling Point
695.9°C at 760 mmHg
Solubility
Soluble in ethanol, methanol, DMF, DMSO
Appearance
White to Off-white Solid
Application
Anti-Bacterial Agents