TETRAHYDROALSTONINE

For Research Use Only.
Category
Alkaloids
Cat.No.
NP0007
CAS
6474-90-4
Product Name
TETRAHYDROALSTONINE
Structure

Product Details

Description
Tetrahydroalstonine may be extracted from the herbs of Uncaria rhynchophylla (Miq.) Miq. ex Havil. Raubasine and Tetrahydroalstonine preferentially block the pressor responses of post-synaptic alpha-adrenergic receptor activation due to endogenous and exogenous noradrenaline, respectively.
Synonyms
ALSTONINE; 20-alpha)-lph; 3,4,5,6-tetrahydro-alstonin; TETRAHYDROALSTONINE; methyl (19alpha,20alpha)-16,17-didehydro-19-methyloxayohimban-16-carboxylate; TETRAHYDROALSTONINE(RG); (20α)-16,17-Didehydro-19α-methyl-18-oxayohimban-16-carboxylic acid methyl ester; 3α,4,5,6-Tetrahydroalstonine
IUPAC Name
methyl (1S,15S,16S,20S)-16-methyl-17-oxa-3,13-diazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4,6,8,18-pentaene-19-carboxylate
Molecular Weight
352.4
Molecular Formula
C21H24N2O3
Canonical SMILES
CC1C2CN3CCC4=C(C3CC2C(=CO1)C(=O)OC)NC5=CC=CC=C45
InChI
InChI=1S/C21H24N2O3/c1-12-16-10-23-8-7-14-13-5-3-4-6-18(13)22-20(14)19(23)9-15(16)17(11-26-12)21(24)25-2/h3-6,11-12,15-16,19,22H,7-10H2,1-2H3/t12-,15-,16-,19-/m0/s1
InChIKey
GRTOGORTSDXSFK-DLLGKBFGSA-N
Boiling Point
524.0±50.0°C (Predicted)
Melting Point
227°C
Purity
>98%
Density
1.30±0.1 g/cm3(Predicted)
Appearance
Solid
Application
Vasodilator Agents
Storage
2-8°C Refrigerator
Color
White to Off-White
EINECS
229-331-0
Form
Powder
MDL
MFCD31745763
Packaging
5 mg
pKa
18.03±0.60(Predicted)
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