Teriflunomide

Inquiry

For Research Use Only.

Size	Price	Stock	Quantity
1 g	$199	In stock

Category

Impurities

Cat.No.

NP3105

CAS

163451-81-8

Product Name

Teriflunomide

Structure

Product Details

Description

Teriflunomide, the active metabolite of leflunomide, is an immunomodulatory drug inhibiting pyrimidine de novo synthesis by blocking the enzyme dihydroorotate dehydrogenase. It inhibits rapidly dividing cells, including activated T cells, and tyrosine kinase enzymes.

Synonyms

Leflunomide Impurity B; A77 1726; A771726; A77-1726; HMR1726; HMR-1726; HMR 1726; N-(4-Trifluoromethylphenyl)-2-cyano-3-hydroxycrotonamide; 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-beuteamide; LEF-M; Leflunomide EP Impurity B; Aubagio; (2Z)-2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide; Femorix

IUPAC Name

(Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide

Molecular Weight

270.21

Molecular Formula

C12H9F3N2O2

Canonical SMILES

CC(=C(C#N)C(=O)NC1=CC=C(C=C1)C(F)(F)F)O

InChI

InChI=1S/C12H9F3N2O2/c1-7(18)10(6-16)11(19)17-9-4-2-8(3-5-9)12(13,14)15/h2-5,18H,1H3,(H,17,19)/b10-7-

InChIKey

UTNUDOFZCWSZMS-YFHOEESVSA-N