Temozolomide

Inquiry

For Research Use Only.

Category

Impurities

Cat.No.

NP2638

CAS

85622-93-1

Product Name

Temozolomide

Structure

Product Details

Description

Temozolomide is an oral chemotherapy drug.The therapeutic benefit of temozolomide depends on its ability to alkylate/methylate DNA, which most often occurs at the N-7 or O-6 positions of guanine residues. This methylation damages the DNA and triggers the death of tumor cells.

Synonyms

Org3770; Org 3770; Org-3770; SCH-52365; SCH52365; SCH 52365; MB39831; MB-39831; MB 39831; RP46161; RP 46161; R-P46161; CCRG81045; TMZ. US brand names: Methazolastone; Temodar. Foreign brand name: Temodal

IUPAC Name

3-methyl-4-oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide

Molecular Weight

194.15

Molecular Formula

C6H6N6O2

Canonical SMILES

CN1C(=O)N2C=NC(=C2N=N1)C(=O)N

InChI

InChI=1S/C6H6N6O2/c1-11-6(14)12-2-8-3(4(7)13)5(12)9-10-11/h2H,1H3,(H2,7,13)

InChIKey

BPEGJWRSRHCHSN-UHFFFAOYSA-N