Telmisartan

For Research Use Only.
Category
Impurities
Cat.No.
NP3429
CAS
144701-48-4
Product Name
Telmisartan
Structure

Product Details

Description
Telmisartan, also called Pritor, a benzimidazole derivative, is an angiotensin II receptor antagonist that can be used to treat hypertension.
in vitro: activates the PPARγ receptor to 25-30% of that produced by the full agonist rosiglitazone (Ki= 3.7 nM)
Synonyms
2-[4-[[4-methyl-6-(1-methylbenzimidazol-2-yl)-2-propylbenzimidazol-1-yl]methyl]phenyl]benzoic acid4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl)methyl)-(1,1'-biphenyl)-2-carboxylic acidBIBR-277; BIBR277; BIBR 277; Telmisartan; Kinzalmono; MicardisMicardisPritortelmisartan
IUPAC Name
2-[4-[[4-methyl-6-(1-methylbenzimidazol-2-yl)-2-propylbenzimidazol-1-yl]methyl]phenyl]benzoic acid
Molecular Weight
514.61
Molecular Formula
C33H30N4O2
Canonical SMILES
CCCC1=NC2=C(C=C(C=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C(=O)O)C5=NC6=CC=CC=C6N5C)C
InChI
1S/C33H30N4O2/c1-4-9-30-35-31-21(2)18-24(32-34-27-12-7-8-13-28(27)36(32)3)19-29(31)37(30)20-22-14-16-23(17-15-22)25-10-5-6-11-26(25)33(38)39/h5-8,10-19H,4,9,20H2,1-3H3,(H,38,39)
InChIKey
RMMXLENWKUUMAY-UHFFFAOYSA-N
Boiling Point
771.9±70.0 °C | Condition: Press: 760 Torr
Melting Point
260-262 °C
Purity
>99%
Density
1.24±0.1 g/cm3
Solubility
Soluble to 13 mg/mL in DMSO, to <1 mg/mL in Water
Appearance
White or off white crystalline powder
Application
An angiotensin II receptor antagonist.
Shelf Life
2 years
Storage
Store in a cool and dry place and at 0 - 4°C for short term (days to weeks) or -63°C for long term (months to years).
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