Telmisartan

Inquiry

For Research Use Only.

Category

Impurities

Cat.No.

NP3429

CAS

144701-48-4

Product Name

Telmisartan

Structure

Product Details

Description

Telmisartan, also called Pritor, a benzimidazole derivative, is an angiotensin II receptor antagonist that can be used to treat hypertension.
in vitro: activates the PPARγ receptor to 25-30% of that produced by the full agonist rosiglitazone (Ki= 3.7 nM)

Synonyms

2-[4-[[4-methyl-6-(1-methylbenzimidazol-2-yl)-2-propylbenzimidazol-1-yl]methyl]phenyl]benzoic acid4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl)methyl)-(1,1'-biphenyl)-2-carboxylic acidBIBR-277; BIBR277; BIBR 277; Telmisartan; Kinzalmono; MicardisMicardisPritortelmisartan

IUPAC Name

2-[4-[[4-methyl-6-(1-methylbenzimidazol-2-yl)-2-propylbenzimidazol-1-yl]methyl]phenyl]benzoic acid

Molecular Weight

514.61

Molecular Formula

C33H30N4O2

Canonical SMILES

CCCC1=NC2=C(C=C(C=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C(=O)O)C5=NC6=CC=CC=C6N5C)C

InChI

1S/C33H30N4O2/c1-4-9-30-35-31-21(2)18-24(32-34-27-12-7-8-13-28(27)36(32)3)19-29(31)37(30)20-22-14-16-23(17-15-22)25-10-5-6-11-26(25)33(38)39/h5-8,10-19H,4,9,20H2,1-3H3,(H,38,39)

InChIKey

RMMXLENWKUUMAY-UHFFFAOYSA-N

Boiling Point

771.9±70.0 °C | Condition: Press: 760 Torr

Melting Point

260-262 °C

Purity

>99%

Density

1.24±0.1 g/cm3

Solubility

Soluble to 13 mg/mL in DMSO, to <1 mg/mL in Water