Tectorigenin

Inquiry

For Research Use Only.

Size	Price	Stock	Quantity
100 mg	$519	In stock

Category

Flavonoids

Cat.No.

NP2537

CAS

548-77-6

Product Name

Tectorigenin

Structure

Product Details

Description

Tectorigenin induced differentiation of human promyelocytic leukemia HL-60 cells to granulocytes and monocytes/macrophages, and caused apoptotic changes of DNA in the cells, as did genistein. Tectorigenin also inhibited autophosphorylation of epidermal growth factor (EGF) receptor by EGF and decreased the expression of Bcl-2 protein, with less activity than genistein. From these results, tectorigenin may be a possible therapeutic agent for leukemia.

Synonyms

5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one; 6-Methoxy-5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 5,7-Dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-chromen-4-one; 4H-1-Benzopyran-4-one, 5,7-dihydroxy-3-(4-hydroxyphenyl)-6-methoxy-; Isoflavone, 4',5,7-trihydroxy-6-methoxy-; 5,7,4'-Trihydroxy-6-methoxyisoflavone; K 251T; Tectrigenin

IUPAC Name

5,7-dihydroxy-3-(4-hydroxyphenyl)-6-methoxychromen-4-one

Molecular Weight

300.26

Molecular Formula

C16H12O6

Canonical SMILES

COC1=C(C2=C(C=C1O)OC=C(C2=O)C3=CC=C(C=C3)O)O

InChI

InChI=1S/C16H12O6/c1-21-16-11(18)6-12-13(15(16)20)14(19)10(7-22-12)8-2-4-9(17)5-3-8/h2-7,17-18,20H,1H3

InChIKey

OBBCRPUNCUPUOS-UHFFFAOYSA-N