Tazobactam acid

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For Research Use Only.

Category

Impurities

Cat.No.

NP3367

CAS

89786-04-9

Product Name

Tazobactam acid

Structure

Product Details

Description

Tazobactam acid is a pharmaceutical drug that inhibits the action of bacterial β-lactamases, especially those belonging to the SHV-1 and TEM groups. It is commonly used as the sodium salt. It is derived from the penicillin nucleus and is a penicillinic acid sulfone. It is used with β-lactam antibiotics to enhance their effect. It has antibacterial activity.

Synonyms

Tazobactam acid; Tazobactamum; Zosyn; CL-298741; YTR-830H

IUPAC Name

(2S,3S,5R)-3-methyl-4,4,7-trioxo-3-(triazol-1-ylmethyl)-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

Molecular Weight

300.29

Molecular Formula

C10H12N4O5S

Canonical SMILES

CC1(C(N2C(S1(=O)=O)CC2=O)C(=O)O)CN3C=CN=N3

InChI

InChI=1S/C10H12N4O5S/c1-10(5-13-3-2-11-12-13)8(9(16)17)14-6(15)4-7(14)20(10,18)19/h2-3,7-8H,4-5H2,1H3,(H,16,17)/t7-,8+,10+/m1/s1

InChIKey

LPQZKKCYTLCDGQ-WEDXCCLWSA-N

Boiling Point

707.1±70.0°C

Melting Point

>170°C (dec.)

Purity

>98%

Density

1.92±0.1 g/cm3

Solubility

Soluble in DMSO (35 mg/mL), Methanol

Appearance

White to Off-white Solid

Application

Anti-Bacterial Agents

Shelf Life

2 month in rt, long time

Storage

Store at -20°C

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