Tazobactam acid

For Research Use Only.
Category
Impurities
Cat.No.
NP3367
CAS
89786-04-9
Product Name
Tazobactam acid
Structure

Product Details

Description
Tazobactam acid is a pharmaceutical drug that inhibits the action of bacterial β-lactamases, especially those belonging to the SHV-1 and TEM groups. It is commonly used as the sodium salt. It is derived from the penicillin nucleus and is a penicillinic acid sulfone. It is used with β-lactam antibiotics to enhance their effect. It has antibacterial activity.
Synonyms
Tazobactam acid; Tazobactamum; Zosyn; CL-298741; YTR-830H
IUPAC Name
(2S,3S,5R)-3-methyl-4,4,7-trioxo-3-(triazol-1-ylmethyl)-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Molecular Weight
300.29
Molecular Formula
C10H12N4O5S
Canonical SMILES
CC1(C(N2C(S1(=O)=O)CC2=O)C(=O)O)CN3C=CN=N3
InChI
InChI=1S/C10H12N4O5S/c1-10(5-13-3-2-11-12-13)8(9(16)17)14-6(15)4-7(14)20(10,18)19/h2-3,7-8H,4-5H2,1H3,(H,16,17)/t7-,8+,10+/m1/s1
InChIKey
LPQZKKCYTLCDGQ-WEDXCCLWSA-N
Boiling Point
707.1±70.0°C
Melting Point
>170°C (dec.)
Purity
>98%
Density
1.92±0.1 g/cm3
Solubility
Soluble in DMSO (35 mg/mL), Methanol
Appearance
White to Off-white Solid
Application
Anti-Bacterial Agents
Shelf Life
2 month in rt, long time
Storage
Store at -20°C
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