Description
Tanshinone IIB isolated from the roots of Salvia miltiorrhiza. It inhibits the uptake of digoxin and vinblastine in membrane vesicles containing PgP or MRP1, moderately stimulates PgP ATPase activity.
Synonyms
(S)-6-(HydroxyMethyl)-1,6-diMethyl-6,7,8,9-tetrahydrophenanthro[1,2-b]furan-10,11-dione
IUPAC Name
(6S)-6-(hydroxymethyl)-1,6-dimethyl-8,9-dihydro-7H-naphtho[1,2-g][1]benzofuran-10,11-dione
Molecular Formula
C19H18O4
Canonical SMILES
CC1=COC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)CO
InChI
InChI=1S/C19H18O4/c1-10-8-23-18-12-5-6-13-11(4-3-7-19(13,2)9-20)15(12)17(22)16(21)14(10)18/h5-6,8,20H,3-4,7,9H2,1-2H3/t19-/m1/s1
InChIKey
XDUXBBDRILEIEZ-LJQANCHMSA-N
Application
neuro-protective; antioxidant;