Talatisamine

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For Research Use Only.

Size	Price	Stock	Quantity
20 mg	$285	In stock

Category

Alkaloids

Cat.No.

NP0443

CAS

20501-56-8

Product Name

Talatisamine

Structure

Product Details

Description

Talatisamine inhibits the enhanced I(K) caused by Aβ40 oligomers, attenuates cytotoxicity of Aβ oligomers by restoring cell viability and suppressing K(+) loss related apoptotic response.

Synonyms

20-Ethyl-1α,16β-dimethoxy-4-(methoxymethyl)aconitane-8,14α-diol

IUPAC Name

11-ethyl-6,16-dimethoxy-13-(methoxymethyl)-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecane-4,8-diol

Molecular Weight

421.57

Molecular Formula

C24H39NO5

Canonical SMILES

CCN1CC2(CCC(C34C2CC(C31)C5(CC(C6CC4C5C6O)OC)O)OC)COC

InChI

InChI=1S/C24H39NO5/c1-5-25-11-22(12-28-2)7-6-18(30-4)24-14-8-13-16(29-3)10-23(27,19(14)20(13)26)15(21(24)25)9-17(22)24/h13-21,26-27H,5-12H2,1-4H3

InChIKey

BDCURAWBZJMFIK-UHFFFAOYSA-N

Boiling Point

533.9±50.0°C (Predicted)

Melting Point

151-152 ºC

Purity

95 % (HPLC).

Density

1.25 g/cm3

Solubility

Chloroform, DMSO

Appearance

Solid powder

Storage

Store at +4 °C, in dark place.

Form

Powder

Packaging

20 mg

pKa

13.65±0.70(Predicted)

Uses

Talatisamine as a versatile antidotes against poisoning of animals and humans by aconitine-, veratridine-, and batrachotoxin-type neurotoxins.

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