Description
Sulochrin is a fungal metabolite isolated from Aspergillus and Penicillium. It has anti-allergic, anti-angiogenic and anti-viral activities. It is an anti-angiogenic agent that can inhibit VEGF, thereby inhibiting the capillary-like formation of human umbilical vein endothelial cells. It also inhibits the activation and chemotaxis of eosinophils.
IUPAC Name
methyl 2-(2,6-dihydroxy-4-methylbenzoyl)-5-hydroxy-3-methoxybenzoate
Molecular Formula
C17H16O7
Canonical SMILES
CC1=CC(=C(C(=C1)O)C(=O)C2=C(C=C(C=C2OC)O)C(=O)OC)O
InChI
InChI=1S/C17H16O7/c1-8-4-11(19)15(12(20)5-8)16(21)14-10(17(22)24-3)6-9(18)7-13(14)23-2/h4-7,18-20H,1-3H3
InChIKey
YJRLSCDUYLRBIZ-UHFFFAOYSA-N
Boiling Point
576.3°C at 760 mmHg
Solubility
Soluble in ethanol, methanol, DMF, DMSO
Appearance
Pale Yellow Solid