Description
Sulfamethazine is a sulfonamide antibacterial agent that competitively inhibits dihydrospteric acid synthase, blocks the synthesis of folic acid and inhibits growth and proliferation. It can be used to treat pasteurosis, mastitis, urinary tract infections caused by sensitive bacteria in livestock, and can also be used for swine atrophic rhinitis, streptococcal disease, swine toxoplasmosis and coccidiosis.
Synonyms
HSDB 4157; HSDB-4157; HSDB4157; Sulfadimidine; Intradine; Kelametazine; 4-Amino-N-(4,6-Dimethyl-2-pyrimidinyl)benzenesulfonamide; Azolmetazin; Diazil
IUPAC Name
4-amino-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide
Molecular Formula
C12H14N4O2S
Canonical SMILES
CC1=CC(=NC(=N1)NS(=O)(=O)C2=CC=C(C=C2)N)C
InChI
InChI=1S/C12H14N4O2S/c1-8-7-9(2)15-12(14-8)16-19(17,18)11-5-3-10(13)4-6-11/h3-7H,13H2,1-2H3,(H,14,15,16)
InChIKey
ASWVTGNCAZCNNR-UHFFFAOYSA-N
Boiling Point
526.2°C at 760 mmHg
Solubility
Slightly soluble in DMSO, Methanol
Appearance
White to Off-white Solid
Application
Anti-infective agents