Sugiol

Inquiry

For Research Use Only.

Category

Diterpenoids

Cat.No.

NP1351

CAS

511-05-7

Product Name

Sugiol

Structure

Product Details

Description

Sugiol is extracted from the herbs of Salvia yunnanensis. It inhibits the inflammatory cytokines of TNF-alpha and IL-1beta by the decrease of the ROS and the reduction in the phosphorylation of MAPKs. It could scaveng activities of nitric oxide, 1,1-diphenyl-2-picryl hydrazyl, hydroxyl free radicals and superoxide significantly. It displays an antioxidant effect.

Synonyms

(4aS,10aS)-6-hydroxy-1,1,4a-trimethyl-7-propan-2-yl-3,4,10,10a-tetrahy dro-2H-phenanthren-9-one; (+)-Sugiol; (4aS)-2,3,4,4a,10,10aα-Hexahydro-6-hydroxy-1,1,4a-trimethyl-7-isopropylphenanthren-9(1H)-one; 12-Hydroxyabieta-8,11,13-triene-7-one; 10-Deoxoxanthoperol

Molecular Weight

300.44

Molecular Formula

C20H28O2

Canonical SMILES

CC(C)C1=C(C=C2C(=C1)C(=O)CC3C2(CCCC3(C)C)C)O

InChI

InChI=1S/C20H28O2/c1-12(2)13-9-14-15(10-16(13)21)20(5)8-6-7-19(3,4)18(20)11-17(14)22/h9-10,12,18,21H,6-8,11H2,1-5H3/t18-,20+/m0/s1

InChIKey

IPEHJNRNYPOFII-AZUAARDMSA-N

Boiling Point

185-205 °C(Press: 0.1 Torr)