Description
Stephanine is isolated from the root of Stephania japonica. It inhibits anococcygeus muscle contraction induced by phenylephrine, so Stephanine is a potent and highly selective alpha 1 adrenoceptor blocker.
Synonyms
8-Methoxy-1,2-methylenedioxyaporphine
IUPAC Name
(12R)-15-methoxy-11-methyl-3,5-dioxa-11-azapentacyclo[10.7.1.02,6.08,20.014,19]icosa-1(20),2(6),7,14(19),15,17-hexaene
Molecular Formula
C19H19NO3
Canonical SMILES
CN1CCC2=CC3=C(C4=C2C1CC5=C4C=CC=C5OC)OCO3
InChI
InChI=1S/C19H19NO3/c1-20-7-6-11-8-16-19(23-10-22-16)18-12-4-3-5-15(21-2)13(12)9-14(20)17(11)18/h3-5,8,14H,6-7,9-10H2,1-2H3/t14-/m1/s1
InChIKey
UEAPAHNNFSZHMW-CQSZACIVSA-N