Sennoside A

Inquiry

For Research Use Only.

Category

Anthraquinones

Cat.No.

NP0906

CAS

81-27-6

Product Name

Sennoside A

Structure

Product Details

Description

Sennoside A, a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine. Sennoside A can be used in health products. It is an HIV-1 inhibitor that is effective against HIV-1 replication.

Synonyms

(R*,R*)-5,5'-Bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo[9,9'-Bianthracene]-2,2'-dicarboxylic Acid; Glysennid; NSC 112929; Senokot; (9R,9'R)-5-(β-D-Glucopyranosyloxy)-5'-(D-glucopyranosyloxy)-4,4'-dihydroxy-10,10'-dioxo-9,9',10,10'-tetrahydro-9,9'-bianthracene-2,2'-dicarboxylic acid; [9,9'-Bianthracene]-2,2'-dicarboxylic acid, 5-(β-D-glucopyranosyloxy)-5'-(D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-, (9R,9'R)-

IUPAC Name

(9R)-9-[(9R)-2-carboxy-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracen-9-yl]-4-hydroxy-10-oxo-5-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-9H-anthracene-2-carboxylic acid

Molecular Weight

862.74

Molecular Formula

C42H38O20

Canonical SMILES

C1=CC2=C(C(=C1)OC3C(C(C(C(O3)CO)O)O)O)C(=O)C4=C(C2C5C6=C(C(=CC=C6)OC7C(C(C(C(O7)CO)O)O)O)C(=O)C8=C5C=C(C=C8O)C(=O)O)C=C(C=C4O)C(=O)O

InChI

InChI=1S/C42H38O20/c43-11-23-31(47)35(51)37(53)41(61-23)59-21-5-1-3-15-25(17-7-13(39(55)56)9-19(45)27(17)33(49)29(15)21)26-16-4-2-6-22(60-42-38(54)36(52)32(48)24(12-44)62-42)30(16)34(50)28-18(26)8-14(40(57)58)10-20(28)46/h1-10,23-26,31-32,35-38,41-48,51-54H,11-12H2,(H,55,56)(H,57,58)/t23-,24-,25-,26-,31-,32-,35+,36+,37-,38-,41-,42-/m1/s1

InChIKey

IPQVTOJGNYVQEO-KGFNBKMBSA-N

Boiling Point

1144.8±65.0°C (Predicted)

Melting Point

>191°C (dec.)

Flash Point

348.6±27.8 °C

Purity

>98%

Density

1.743±0.06 g/cm3 (Predicted)