Scopoletin

Inquiry

For Research Use Only.

Category

Coumarins

Cat.No.

NP1014

CAS

92-61-5

Product Name

Scopoletin

Structure

Product Details

Description

Scopoletin, that comes from the herbs of Atropa belladonna L, can ameliorate alcohol-induced hepatic lipid accumulation by modulating AMPK-SREBP pathway-mediated lipogenesis in mice fed a high-fat diet. Scopoletin exerts anti-RA action probably through suppressing IL-6 production from fibroblast-like synoviocytes via MAPK/PKC/CREB pathways. Besiedes, the anti-allergic properties of Scopoletin might be mediated by the downregulation of cytokine expression in Th 2 cells.

Synonyms

Gelseminic acid; 7-Hydroxy-6-methoxy-2H-chromen-2-one; 6-Methylesculetin; Chrysatropic acid; Murrayetin; 6-O-Methylesculetin

IUPAC Name

7-hydroxy-6-methoxychromen-2-one

Molecular Weight

192.17

Molecular Formula

C10H8O4

Canonical SMILES

COC1=C(C=C2C(=C1)C=CC(=O)O2)O

InChI

InChI=1S/C10H8O4/c1-13-9-4-6-2-3-10(12)14-8(6)5-7(9)11/h2-5,11H,1H3