Sclareol glycol

Diterpenoids

NP1525

38419-75-9

Sclareol glycol

Sclareol glycol is extracted from the plants of Salvia sclarea L. It has anxiogenic, adaptogenic and memory-facilitator effects and was mediated by different mechanisms of action such as interaction with GABA-ergic, stimulation of adenylate cyclase and dopaminergic transmitter. It inhibits clonidine-induced aggressive behavior via its effect on adenylate cyclase and perhaps involving synaptic transmitter action. It induces changes in core body temperature by interacting with the second messenger system of 3',5'-AMP in the brain thermoregulatory areas and with dopamine (DA) receptors.

1-Naphthaleneethanol, decahydro-2-hydroxy-2,5,5,8a-tetramethyl-, (1R,2R,4aS,8aS)-; (1R,2R,4aS,8aS)-Decahydro-2-hydroxy-2,5,5,8a-tetramethyl-1-naphthaleneethanol; 1-Naphthaleneethanol, decahydro-2-hydroxy-2,5,5,8a-tetramethyl-, [1R-(1α,2β,4aβ,8aα)]-; (-)-13,14,15,16-Tetranorlabdane-8α,12-diol; (-)-Sclareoldiol; 13,14,15,16-Tetranorlabdane-8,12-diol; 13,14,15,16-Tetranorlabdane-8α,12-diol; 8α,12-Dihydroxy-13,14,15,16-tetranorlabdane; Ambroxdiol; AT 1; Sukurarerin

(1R,2R,4aS,8aS)-1-(2-hydroxyethyl)-2,5,5,8a-tetramethyl-3,4,4a,6,7,8-hexahydro-1H-naphthalen-2-ol

254.41

C16H30O2

CC1(CCCC2(C1CCC(C2CCO)(C)O)C)C

InChI=1S/C16H30O2/c1-14(2)8-5-9-15(3)12(14)6-10-16(4,18)13(15)7-11-17/h12-13,17-18H,5-11H2,1-4H3/t12-,13+,15-,16+/m0/s1

AIALTZSQORJYNJ-LQKXBSAESA-N

315.3±10.0°C at 760 mmHg

132.2-133.0°C

99.0%

0.970±0.06 g/cm3

Soluble in Acetone, Chloroform, Dichloromethane, DMSO, Ethyl Acetate

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Store at -20°C

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