Description
Schisandrin B, a dibenzocyclooctadiene derivative isolated from Schisandra propinqua and Schisandra rubriflora, has antioxidant effects on the liver and heart of rodents. It is used in traditional Chinese medicine to treat hepatitis and myocardial disorders. The anti-inflammatory effect of Schisandrin B is mediated by regulating Nrf2 and NF-κB in lymphocytes.
Synonyms
rel-(6R,7S,13aR)-5,6,7,8-Tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethylbenzo[3,4]cycloocta[1,2-f][1,3]benzodioxole; (±)-γ-Schisandrin; γ-Schizandrin; (±)-γ-Schizandrin; Schisandrin B; Wuweizisu B; gamma-Schisandrin; γ-Schisandrin; Benzo[3,4]cycloocta[1,2-f][1,3]benzodioxole, 5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-, (6R,7S,13aR)-rel-; Sch B
IUPAC Name
3,4,5,19-tetramethoxy-9,10-dimethyl-15,17-dioxatetracyclo[10.7.0.02,7.014,18]nonadeca-1(19),2,4,6,12,14(18)-hexaene
Molecular Formula
C23H28O6
Canonical SMILES
CC1CC2=CC3=C(C(=C2C4=C(C(=C(C=C4CC1C)OC)OC)OC)OC)OCO3
InChI
InChI=1S/C23H28O6/c1-12-7-14-9-16(24-3)20(25-4)22(26-5)18(14)19-15(8-13(12)2)10-17-21(23(19)27-6)29-11-28-17/h9-10,12-13H,7-8,11H2,1-6H3
InChIKey
RTZKSTLPRTWFEV-UHFFFAOYSA-N
Boiling Point
545.0±50.0°C (Predicted)
Density
1.148±0.06 g/cm3 (Predicted)