Sarsasapogenin

Inquiry

For Research Use Only.

Category

Steroids

Cat.No.

NP6105

CAS

126-19-2

Product Name

Sarsasapogenin

Structure

Product Details

Description

Sarsasapogenin, that can be found in the rhizomes of Anemarrhena asphodeloides Bunge, exhibited antitumor activity by inducing apoptosis in vitro as determined by Hoechst staining analysis and double staining of Annexin V-FITC/PI. Most of the Sarsasapogenin derivatives displayed excellent selective cytotoxicity toward the cancer cell lines.

Synonyms

Spirostan-3-ol, (3β,5β,25S)-; (3β,5β,25S)-Spirostan-3-ol; 5β-Spirostan-3β-ol, (25S)-; Parigenin; Sarsagenin; Yucconin; (2aR,4S,5'S,6aS,6bS,8aS,8bR,9S,10R,11aS,12aS,12bR)-5',6a,8a,9-tetramethyldocosahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-pyran]-4-ol; (25S)-5β-spirostan-3β-ol

IUPAC Name

(1R,2S,4S,5'S,6R,7S,8R,9S,12S,13S,16S,18R)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosane-6,2'-oxane]-16-ol

Molecular Weight

416.64

Molecular Formula

C27H44O3

Canonical SMILES

CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)OC1

InChI

InChI=1S/C27H44O3/c1-16-7-12-27(29-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(28)8-10-25(18,3)21(20)9-11-26(22,24)4/h16-24,28H,5-15H2,1-4H3/t16-,17-,18+,19-,20+,21-,22-,23-,24-,25-,26-,27+/m0/s1

InChIKey

GMBQZIIUCVWOCD-WWASVFFGSA-N

Boiling Point

516.6±20.0°C at 760 mmHg

Melting Point

>187°C (dec.)

Purity

>98%

Density

1.11±0.1 g/cm3

Solubility

Soluble in Chloroform (Slightly), Methanol (Slightly)