Description
Sarpagine is a natural alkaloid found in the roots of Alstonia yunnanensis Diels, it is effective in reversing multidrug-resistance (MDR) in vincristine-resistant KB cells.
Synonyms
Sarpagan-10,17-diol;Raupine;Sarpagane-10,17-diol
Molecular Formula
C19H22N2O2
Boiling Point
450.55°C (rough estimate)
Density
1.1396 g/cm3(rough estimate)
Alpha
D20 +54° (c = 0.5 in pyridine)
Definition
ChEBI: An indole alkaloid that is sarpagan bearing hydroxy groups at positions 10 and 17.
pKa
10.24±0.40(Predicted)
Refractive Index
1.5600 (estimate)