Salvianolic acid B

For Research Use Only.
Category
Phenols
Cat.No.
NP4637
CAS
121521-90-2
Product Name
Salvianolic acid B
Structure

Product Details

Description
Source from root of Salvia miltiorrhiza Bge. It showed a protective action against the ischemia-reperfusion induced injury in rat brain by reducing lipid peroxides, scavenging free radicals and improving the energy metabolism. And it has been considered that cerebral endothelium apoptosis caused by reactive oxygen species including hydrogen peroxide (H2O2) is implicated in the pathogenesis of cerebrovascular disorders.
Synonyms
[2R-[2a,3b-(R*),4[E(R*)]]]-3-Benzofurancarboxylic acid 4-[3-[1-carboxy-2-(3,4-dihydroxy-phenyl) ethoxy]-3-oxo-1-propenyl]-2-(3,4-dihydrophenyl)-2,3-dihydro-7-hydroxyl-3-[1-carboxy-2-(3,4-dihydroxyphenyl) ethyl] ester
Molecular Weight
718.62
Molecular Formula
C36H30O16
Canonical SMILES
C1=CC(=C(C=C1CC(C(=O)O)OC(=O)C=CC2=C3C(C(OC3=C(C=C2)O)C4=CC(=C(C=C4)O)O)C(=O)OC(CC5=CC(=C(C=C5)O)O)C(=O)O)O)O
InChI
InChI=1S/C36H30O16/c37-20-6-1-16(11-24(20)41)13-27(34(45)46)50-29(44)10-5-18-3-9-23(40)33-30(18)31(32(52-33)19-4-8-22(39)26(43)15-19)36(49)51-28(35(47)48)14-17-2-7-21(38)25(42)12-17/h1-12,15,27-28,31-32,37-43H,13-14H2,(H,45,46)(H,47,48)/b10-5+/t27-,28+,31
InChIKey
SNKFFCBZYFGCQN-SGAFACQOSA-N
Boiling Point
1020.3±65.0 °C(Predicted)
Melting Point
98-110°C
Purity
>98%
Density
1.637±0.06 g/cm3(Predicted)
Solubility
20 mg/mL in DMSO
Appearance
Powder
Application
It showed a protective action against the ischemia-reperfusion induced injury in rat brain by reducing lipid peroxides, scavenging free radicals and improving the energy metabolism. And it has been considered that cerebral endothelium apoptosis caused by
Shelf Life
As supplied, 2 years from the QC date provided on the Certificate of Analysis, when stored properly
Storage
-20ºC Freeze
Chemical Properties
Yellow Solid
Color
White to tan
Form
powder
HS Code
29329990
MDL
MFCD23115783
NACRES
NA.77
pKa
2.77±0.10(Predicted)
RTECS
DF6492107
Safety Statements
24/25
Uses
Salvianolic acid A (Sal A) and salvianolic acid B (Sal B) were isolated and purified from the crude extract of Salvia miltiorrhiza.
Water Solubility
H2O: ≥5mg/mL
WGK Germany
3
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