Rosiglitazone maleate

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For Research Use Only.

Category

Impurities

Cat.No.

NP3380

CAS

155141-29-0

Product Name

Rosiglitazone maleate

Structure

Product Details

Description

Rosiglitazone exhibits insulin-sensitising activity 60- to 200-fold higher than that of troglitazone, englitazone, or piogliazone in rodent models of insulin ressitance.

Synonyms

Rosiglitazone Maleate; Avandia; Avandaryl; BRL-49653C; BRL49653C; BRL 49653C; BRL-49653-C;

IUPAC Name

(Z)-but-2-enedioic acid;5-[[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione

Molecular Weight

473.5

Molecular Formula

C18H19N3O3S.C4H4O4

Canonical SMILES

CN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3.C(=CC(=O)O)C(=O)O

InChI

InChI=1S/C18H19N3O3S.C4H4O4/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15;5-3(6)1-2-4(7)8/h2-9,15H,10-12H2,1H3,(H,20,22,23);1-2H,(H,5,6)(H,7,8)/b;2-1-

InChIKey

SUFUKZSWUHZXAV-BTJKTKAUSA-N

Melting Point

121-123 ℃

Purity

>98%

Solubility

68.2 [ug/mL] (The mean of the results at pH 7.4)

Appearance

White to Off-White Solid

Application

Hypoglycemic Agents

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