Rosiglitazone

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For Research Use Only.

Category

Impurities

Cat.No.

NP3495

CAS

122320-73-4

Product Name

Rosiglitazone

Structure

Product Details

Description

Rosiglitazone is a potent antihyperglycemic agent and a potent thiazolidinedione insulin sensitizer with IC50 of 12, 4 and 9 nM for rat, 3T3-L1 and human adipocytes, respectively.

Synonyms

BRL49653; BRL-49653; BRL 49653; HSDB 7555; HSDB-7555; HSDB7555; TDZ 01; TDZ-01; TDZ01; Rosiglitazone. trade name Avandia.

Molecular Weight

357.43

Molecular Formula

C18H19N3O3S

Canonical SMILES

CN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3

InChI

InChI=1S/C18H19N3O3S/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15/h2-9,15H,10-12H2,1H3,(H,20,22,23)

InChIKey

YASAKCUCGLMORW-UHFFFAOYSA-N

Melting Point

155-156°C

Purity

>98%

Appearance

White to Off-white Solid

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