Rifampicin

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For Research Use Only.

Size	Price	Stock	Quantity
100 g	$398	In stock

Category

Impurities

Cat.No.

NP3702

CAS

13292-46-1

Product Name

Rifampicin

Structure

Product Details

Description

It is a semi-synthetic antibiotic of the rifamycin group. It is an inhibitor of bacterial RNA polymerase and has antibacerial activity.

Synonyms

Rimactane; 3-[[(4-Methyl-1-piperazin-yl)imino]methyl]rifamycin; Abrifam; Eremfat; Famcin; NSC 113926; Rifa; Rifacap; Rifadin; Rifadine; Rifaldazine; Rifampicin SV; Rifamycin AMP; Rifaprodin; Rifoldin; Riforal; Rimactan; Rimactane; Rimapen; Sinerdol; Tubocin

IUPAC Name

[(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-26-[(E)-(4-methylpiperazin-1-yl)iminomethyl]-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(29),2,4,9,19,21,25,27-octaen-13-yl] acetate

Molecular Weight

822.94

Molecular Formula

C43H58N4O12

Canonical SMILES

CC1C=CC=C(C(=O)NC2=C(C(=C3C(=C2O)C(=C(C4=C3C(=O)C(O4)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C)O)O)C=NN5CCN(CC5)C)C

InChI

InChI=1S/C43H58N4O12/c1-21-12-11-13-22(2)42(55)45-33-28(20-44-47-17-15-46(9)16-18-47)37(52)30-31(38(33)53)36(51)26(6)40-32(30)41(54)43(8,59-40)57-19-14-29(56-10)23(3)39(58-27(7)48)25(5)35(50)24(4)34(21)49/h11-14,19-21,23-25,29,34-35,39,49-53H,15-18H2,1-10H3,(H,45,55)/b12-11+,19-14+,22-13-,44-20+/t21-,23+,24+,25+,29-,34-,35+,39+,43-/m0/s1

InChIKey

JQXXHWHPUNPDRT-WLSIYKJHSA-N

Boiling Point

1004.42°C at 760 mmHg

Melting Point

>180°C (dec.)

Flash Point

561.3±34.3 °C

Purity

98%

Density

1.34 g/cm3

Solubility

Soluble in Chloroform, DMSO, Methanol

Appearance

Brownish-red Crystalline Powder

Application

Antibiotics, Antitubercular; enzyme inhibitors; leprostatic agents; nucleic acid synthesis inhibitors

Storage

Store at RT

Toxicity

LD50: 1570 mg/kg (Rat).

Vapor Pressure

0.0±0.3 mmHg at 25°C

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