Description
Rhapontigenin is a natural analog of resveratrol and an inhibitor of cytochrome P450 1A1 (IC50 = 400 nM). It exhibits antioxidant and anticancer activity. At higher concentrations, rhapontigenin inhibits the proliferation of HepG2 and HL-60R cancer cell lines (IC50 = 48 μM).
Synonyms
Protigenin; (E)-5-(3-Hydroxy-4-methoxystyryl)benzene-1,3-diol; 5-[(E)-2-(3-hydroxy-4-methoxyphenyl)ethenyl]benzene-1,3-diol
IUPAC Name
5-[(E)-2-(3-hydroxy-4-methoxyphenyl)ethenyl]benzene-1,3-diol
Molecular Formula
C15H14O4
Canonical SMILES
COC1=C(C=C(C=C1)C=CC2=CC(=CC(=C2)O)O)O
InChI
InChI=1S/C15H14O4/c1-19-15-5-4-10(8-14(15)18)2-3-11-6-12(16)9-13(17)7-11/h2-9,16-18H,1H3/b3-2+
InChIKey
PHMHDRYYFAYWEG-NSCUHMNNSA-N
Appearance
Crystalline Solid