Questinol

Inquiry

For Research Use Only.

Category

Anthraquinones

Cat.No.

NP0899

CAS

35688-09-6

Product Name

Questinol

Structure

Product Details

Description

Questinol is obtained from the cultures of the fungus Talaromyces stipitatus KUFA 0207. It can inhibit the production of NO, PGE2 and pro-inflammatory cytokines, including TNF-α, IL-1β and IL-6. It displays anti-inflammatory effect in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. It also shows remarkable anti-obesity activity.

Synonyms

1,6-Dihydroxy-3-(hydroxymethyl)-8-methoxy-9,10-anthracenedione; 9,10-Anthracenedione, 1,6-dihydroxy-3-(hydroxymethyl)-8-methoxy-; Omega-Hydroxymethylemodin

IUPAC Name

1,6-dihydroxy-3-(hydroxymethyl)-8-methoxyanthracene-9,10-dione

Molecular Weight

300.26

Molecular Formula

C16H12O6

Canonical SMILES

COC1=C2C(=CC(=C1)O)C(=O)C3=CC(=CC(=C3C2=O)O)CO

InChI

InChI=1S/C16H12O6/c1-22-12-5-8(18)4-10-14(12)16(21)13-9(15(10)20)2-7(6-17)3-11(13)19/h2-5,17-19H,6H2,1H3

InChIKey

SNBGJGNOQURXCI-UHFFFAOYSA-N

Boiling Point

630.5±55.0°C at 760 mmHg

Melting Point

280-282°C

Purity

98.0%

Density

1.5±0.1 g/cm3

Solubility

Soluble in Ethanol

Appearance

Yellow Crystal

Storage

Store at -20°C

Form

Powder

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