Questinol

For Research Use Only.
Category
Anthraquinones
Cat.No.
NP0899
CAS
35688-09-6
Product Name
Questinol
Structure
Structure

Product Details

Description
Questinol is obtained from the cultures of the fungus Talaromyces stipitatus KUFA 0207. It can inhibit the production of NO, PGE2 and pro-inflammatory cytokines, including TNF-α, IL-1β and IL-6. It displays anti-inflammatory effect in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. It also shows remarkable anti-obesity activity.
Synonyms
1,6-Dihydroxy-3-(hydroxymethyl)-8-methoxy-9,10-anthracenedione; 9,10-Anthracenedione, 1,6-dihydroxy-3-(hydroxymethyl)-8-methoxy-; Omega-Hydroxymethylemodin
IUPAC Name
1,6-dihydroxy-3-(hydroxymethyl)-8-methoxyanthracene-9,10-dione
Molecular Weight
300.26
Molecular Formula
C16H12O6
Canonical SMILES
COC1=C2C(=CC(=C1)O)C(=O)C3=CC(=CC(=C3C2=O)O)CO
InChI
InChI=1S/C16H12O6/c1-22-12-5-8(18)4-10-14(12)16(21)13-9(15(10)20)2-7(6-17)3-11(13)19/h2-5,17-19H,6H2,1H3
InChIKey
SNBGJGNOQURXCI-UHFFFAOYSA-N
Boiling Point
630.5±55.0°C at 760 mmHg
Melting Point
280-282°C
Purity
98.0%
Density
1.5±0.1 g/cm3
Solubility
Soluble in Ethanol
Appearance
Yellow Crystal
Storage
Store at -20°C
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