Questin

Anthraquinones

NP0898

3774-64-9

Questin

Questin is extracted from the seeds of Cassia obtusifolia. It is a Cdc25B phosphatase inhibitor with the IC50 value of 34 microg/mL. It is also a promising inhibitor for AChE, BChE, and BACE1. It also strongly inhibited the growth of human colon cancer cells, SW620 with the GI(50) value of 0.9 microg/mL. It displays considerably high immunosuppressive activity and may be used as a therapeutic or preventive agent for Alzheimer's disease. It is toxic to the human A549 lung cell line.

1,6-Dihydroxy-3-methyl-8-methoxy-9,10-anthraquinone; Emodin-8-methyl ether; 1,6-Dihydroxy-8-methoxy-3-methylanthracene-9,10-dione

1,6-dihydroxy-8-methoxy-3-methylanthracene-9,10-dione

284.26

C16H12O5

CC1=CC(=C2C(=C1)C(=O)C3=CC(=CC(=C3C2=O)OC)O)O

InChI=1S/C16H12O5/c1-7-3-9-13(11(18)4-7)16(20)14-10(15(9)19)5-8(17)6-12(14)21-2/h3-6,17-18H,1-2H3

UUNPIWCQMVNINR-UHFFFAOYSA-N

97.5%

Orange powder

Powder