Description
Quassin is a natural diterpenoid found in the barks of Quassia amara L. It exhibits anti-larval activity at a concentration of 6 ppm.
Synonyms
Picrasa-2,12-diene-1,11,16-trione, 2,12-dimethoxy-
IUPAC Name
(1S,2S,6S,7S,9R,13R,17S)-4,15-dimethoxy-2,6,14,17-tetramethyl-10-oxatetracyclo[7.7.1.02,7.013,17]heptadeca-4,14-diene-3,11,16-trione
Molecular Formula
C22H28O6
Canonical SMILES
CC1C=C(C(=O)C2(C1CC3C4(C2C(=O)C(=C(C4CC(=O)O3)C)OC)C)C)OC
InChI
InChI=1S/C22H28O6/c1-10-7-14(26-5)20(25)22(4)12(10)8-15-21(3)13(9-16(23)28-15)11(2)18(27-6)17(24)19(21)22/h7,10,12-13,15,19H,8-9H2,1-6H3/t10-,12+,13+,15-,19+,21-,22+/m1/s1
InChIKey
IOSXSVZRTUWBHC-LBTVDEKVSA-N
Boiling Point
586.3±50.0 °C(Predicted)
Solubility
Chloroform (Slightly), methanol (Slightly)
Storage
-20°C Freezer, Under inert atmosphere
Alpha
D20 +34.5° (c = 5.09 in CHCl3)
Uses
Quassin is a naturally occurring extract from quassia trees and is used in traditional chinese medicine for its antiulcerogenic properties. Quassin have also been used as an additive in soft drinks.