Description
Puerol A is isolated from the stem bark of Sophora japonica. Puerol A has antioxdiant activity that inhibits copper ion-induced protein oxidative modification of mouse brain homogenate in vitro. Puerol A shows potent inhibitory effects on aldose reductase with IC50 values of 6.4 uM.
Synonyms
3-(2,4-dihydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]-2H-furan-5-one
Molecular Formula
C17H14O5
Canonical SMILES
C1=CC(=CC=C1CC2C(=CC(=O)O2)C3=C(C=C(C=C3)O)O)O
InChI
InChI=1S/C17H14O5/c18-11-3-1-10(2-4-11)7-16-14(9-17(21)22-16)13-6-5-12(19)8-15(13)20/h1-6,8-9,16,18-20H,7H2
InChIKey
AYXZYYUMEUUTRQ-UHFFFAOYSA-N