Psoralidin

For Research Use Only.
Category
Coumarins
Cat.No.
NP1133
CAS
18642-23-4
Product Name
Psoralidin
Structure

Product Details

Description
Psoralidin is a furanocoumarin natural product used in Chinese medicine. Psoralidin, a PTP1B inhibitor, has been shown to have anticancer activity with a variety of mechanisms proposed. Psoralidin induces ROS generation in androgen-independent prostate cancer cells, leading to inhibition of cell proliferation. Psoralidin has been found to downregulate NOTCH1 signaling, causing growth arrest in both breast cancer stem cells and breast cancer cells.
Synonyms
3,9-Dihydroxy-2-(3-methyl-2-butenyl)-6H-benzofuro[3,2-c][1]benzopyran-6-one; 3,9-Dihydroxy-2-prenylcoumestan
IUPAC Name
3,9-dihydroxy-2-(3-methylbut-2-enyl)-[1]benzofuro[3,2-c]chromen-6-one
Molecular Weight
336.34
Molecular Formula
C20H16O5
Canonical SMILES
CC(=CCC1=C(C=C2C(=C1)C3=C(C4=C(O3)C=C(C=C4)O)C(=O)O2)O)C
InChI
InChI=1S/C20H16O5/c1-10(2)3-4-11-7-14-17(9-15(11)22)25-20(23)18-13-6-5-12(21)8-16(13)24-19(14)18/h3,5-9,21-22H,4H2,1-2H3
InChIKey
YABIJLLNNFURIJ-UHFFFAOYSA-N
Purity
>98%
Density
1.383g/cm3
Appearance
Powder
Application
anticancer and chemopreventive properties
Form
Powder
Packaging
25 mg
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